Condition Guide
Treatment-Resistant Depression in Utah — Ketamine, Spravato & IOP
You've tried multiple SSRIs. Maybe an SNRI, maybe a mood stabilizer. You're tired of the lag, the side effects, and the feeling that nothing actually moves. CPS offers the next tier of evidence-based care — including ketamine and FDA-approved Spravato.
Who This Is For
- Adults who have failed at least two antidepressant trials
- People whose depression returns every time they taper medication
- Patients whose depression co-occurs with suicidality and need rapid relief
- Those exploring alternatives to or alongside traditional psychiatry
Signs to Watch For
- Persistent depression despite medication and therapy
- Anhedonia — nothing feels rewarding or interesting
- Chronic fatigue, hopelessness, or 'flat' affect
- Suicidal ideation that medication hasn't resolved
- A pattern of brief remission followed by full relapse
Want to know if an evaluation is right for you?
Our intake team will walk you through insurance, scheduling, and what to expect.
How CPS Evaluates Treatment-Resistant Depression
- 1Psychiatric evaluation and medication-history review
- 2Rule-out for bipolar, ADHD, trauma, and medical causes
- 3Suicide-risk assessment and safety planning
- 4Treatment-resistance staging (Maudsley or Thase-Rush)
- 5Candidacy review for ketamine, Spravato, and IOP
Treatment Options at CPS
Frequently Asked
About Treatment-Resistant Depression
Is ketamine safe and FDA-approved for depression?
Spravato (esketamine) is FDA-approved for treatment-resistant depression. IV ketamine is used off-label under careful medical supervision, with strong evidence for rapid antidepressant effects.
Will insurance cover ketamine or Spravato?
Spravato is covered by most major insurance plans for qualifying patients. IV ketamine coverage varies. Our office verifies benefits before treatment.
How fast does ketamine work compared to antidepressants?
Many patients report meaningful mood improvement within hours to days of the first infusion — compared to 4–8 weeks for traditional antidepressants.
Ready to get a clear answer about Treatment-Resistant Depression?
CPS has served Utah since 1986. Call us and our intake team will verify your insurance, match you with the right specialist, and schedule your first appointment.